Pharmaceutical preparation for percutaneous administration conta

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514547, 514552, 514929, A61K 3155, A61K 31225, A61K 3123

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active

050414372

ABSTRACT:
A pharmaceutical composition comprises (a) a pharmacologically effective amount of bunazosin or a pharmacologically acceptable salt thereof and (b) a monoglyceride of a fatty acid having 8 to 12 carbon atoms and/or a lactic acid ester of an aliphatic alcohol having 12 to 18 carbon atoms and is improved in percutaneous administration. ##STR1##

REFERENCES:
patent: 4377581 (1983-03-01), Hess et al.
patent: 4925837 (1990-05-01), Cavaero et al.
J. Pharm. Pharmacol. vol. 39, 1987, pp. 399-400, A. Kato et al., "Effect of Egg Yolk Lecithin on Transdermal Delivery of Bunazosin Hydrochloride".
Chemical Abstracts, vol. 111, No. 12, No. 102753a (1989).

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