Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1989-10-27
1991-08-20
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514547, 514552, 514929, A61K 3155, A61K 31225, A61K 3123
Patent
active
050414372
ABSTRACT:
A pharmaceutical composition comprises (a) a pharmacologically effective amount of bunazosin or a pharmacologically acceptable salt thereof and (b) a monoglyceride of a fatty acid having 8 to 12 carbon atoms and/or a lactic acid ester of an aliphatic alcohol having 12 to 18 carbon atoms and is improved in percutaneous administration. ##STR1##
REFERENCES:
patent: 4377581 (1983-03-01), Hess et al.
patent: 4925837 (1990-05-01), Cavaero et al.
J. Pharm. Pharmacol. vol. 39, 1987, pp. 399-400, A. Kato et al., "Effect of Egg Yolk Lecithin on Transdermal Delivery of Bunazosin Hydrochloride".
Chemical Abstracts, vol. 111, No. 12, No. 102753a (1989).
Asakawa Hidenori
Fujimori Hiroyuki
Kasai Masayoshi
Kayano Masanori
Osawa Shigemitsu
Eisai Co. Ltd.
Hollinden Gary E.
Raymond Richard L.
Sansho Co., Ltd.
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