Pharmaceutical preparation for improving the bioavailability of

Details Pharmaceutical preparation for improving the bioavailability of Pharmaceutical preparation for improving the bioavailability of

1994-07-21

1998-04-07

Spear, James M.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424458, 424459, 424461, 424463, 424490, 424498, 514777, 514775, 514780, 514779, 514782, 514784, A61K 916, A61K 950, A61K 954, A61K 962

Patent

active

057361614

ABSTRACT:
The preparation consists of millispheres, microspheres, nanospheres or array-type particles consisting of a nucleus of a gellable hydrocolloid onto which has been deposited a film of a cationic polysaccharide, and incorporating inside a pharmacologically useful drug. The procedure consists of dissolving, suspending or emulsifying the drug in a solution of the gellable hydrocolloid; adding the resulting mixture to a gelling solution; and suspending the resulting millispheres, microspheres, nanospheres or array-type particles in a solution of the cationic polysaccharide.

REFERENCES:
patent: 5215757 (1993-06-01), El-Nokaly

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