Pharmaceutical preparation containing magnetic vesicular...

Details Pharmaceutical preparation containing magnetic vesicular... Pharmaceutical preparation containing magnetic vesicular...

2005-11-07

2008-09-23

Hartley, Michael G. (Department: 1618)

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

C424S001110

Reexamination Certificate

active

07427393

ABSTRACT:
A pharmaceutical preparation containing magnetic vesicular particles is disclosed, wherein the magnetic vesicular particles each include magnetic microparticles within a lipid membrane, an organic compound having at least two groups selected from the group consisting of a hydroxyl group, a carboxyl group, a carbamoyl group, an amino group, a mercapto group, a sulfo group, a dithio group, a thiocarboxyl group and a dithiocarboxyl group is bonded to the magnetic microparticle, and the magnetic vesicular particles satisfy the following equation:in-line-formulae description="In-line Formulae" end="lead"?0.05≦R/(r×100)≦1.5in-line-formulae description="In-line Formulae" end="tail"?wherein R represents an average grain size of the magnetic vesicular particles and r represents an average particle size of magnetic microparticles included in the magnetic vesicular particles.

REFERENCES:
patent: 5411730 (1995-05-01), Kirpotin et al.
patent: 5753477 (1998-05-01), Chan
patent: 2003/0211045 (2003-11-01), Leszcyznska et al.

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