Pharmaceutical preparation and method for treatment of diabetes

Details Pharmaceutical preparation and method for treatment of diabetes Pharmaceutical preparation and method for treatment of diabetes

2005-06-21

2005-06-21

Wilson, James O. (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S053000, C514S054000, C514S866000

Reexamination Certificate

active

06908904

ABSTRACT:
A method for treatment of a diabetic condition, wherein a therapeutically effective amount of at least one isoform of sulfatide is administered to a patient, wherein said at least one isoform of sulfatide upon administration to the patient affects the sulfatide metabolism in such a way that it results in an increased amount of sulfatide.Also the use of at least one isoform of sulfatide for the production of a pharmaceutical preparation for treatment of a diabetic condition is disclosed.Said isoform is preferably an isoform with 8-24 carbon atoms in the fatty acid chain, more preferably 12, 14, 16 or 18 carbon atoms, and most preferably 16 carbon atoms.

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“Prediabetes”, The American Heritage Dictionary of the English Language Online Edition: 4thEdition, 2000.
Diabetologia, vol. 42, 1999, K. Buschard et al., “Inhibition of insulin-specific autoreactive T-cells by sulphatide which is variably expressed in beta cells” pp. 1212 to 1218.
Dialog Information Services, File 73, EMBASE, Dialog accession No. 6116895, EMBASE accession No. 1995147628, Buschard K. et al., “Neonatal treatment of BB rats with sulphatide delays development of diabetes but does not change incidence” (APMIS), (Denmark) 1995, 103/3 (193-196).

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