Pharmaceutical preparation

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 4, 514 3, 530303, 530307, 530311, 530313, A01N 3718, A61K 3700, C07K 500, C07K 700

Patent

active

053977718

ABSTRACT:
A pharmaceutical preparation for application of an effective amount of one or more biologically active substance(s) to a mucosal membrane of a mammal comprising an n-glycofurol represented by the formula I: ##STR1## wherein n is 1 to 4 in an amount from: 0.1-30% preferably 0.1-20% most preferably 1-15% in water, or in vegetable oil or n-ethylene glycol(s) represented by formula II:

REFERENCES:
patent: 4153689 (1979-05-01), Hirai et al.
Jeppsson et al., "Anticonvulsant Activity in Mice of Diazepam in am Emulsion Formulation for Intravenous Administration," Acta Pharmacol. et Toxicol., 36 (1975) pp. 312-320.
Knudsen, "Plasma-Diazepam in Infants After Rectal Administration in Solution and by Suppository," Acta Paediatr Scand., 66 (1977) pp. 563-567.
DeFlines, "Bereiding van een diazepam-clysma", Pharmaceutisch Weekblad, 114 (1979) p. 805.
Spiegelbert et al., "Ein Neues Injizierbares Losungsmittel (Glycofurol)" 6 Jahrgang, s.75.
Moolenaar et al., "Biopharmaceutics of Rectal Administration of Drugs in Man IX . . . ", International Journal of Pharmaceutics, 5 (1980) pp. 127-137.
Kromann et al., "Diazepam in an Oil Emulsion", Letters to the Editor, 61, No. 6 (1982) p. 544.
Moolenaar et al., "Rectale Irritatie van Vehiculae . . . ", Pharmaceutisch Weekblad, 116 (1981) pp. 33-34.
Yasaka et al., "Mechanisms in the Potentiation and Inhibition of Pharmacological Actions of Hexobarbital and Zoxazolamine by Glycofurol," Biochemical Pharmacology, 27 (1978) pp. 2851-2858).
Illum, "Drug Delivery Systems for Nasal Application", Archiv for Pharmaci og Chemi, 94 (1987) pp. 127-135.
Morimoto et al., "Nasal Absorption of Nifedipine from Gel Preparations in Rats", Chem. Pharm. Bull., 35/7, (1987) pp. 3041-3044.
Lau et al., "Absorption of Diazepam and Lorazepam Following Intranasal Administration", International Journal of Pharmaceutics, 54 (1989) pp. 171-174.
PCT/US89/03897--WO 90/02737 (Goldberg).
PCT/AT87/00015--WO 87/05210 (Burghart).
PCT/EP89/01186--WO 90/03796 (Schiapparelli).
PCT/US89/05260--WO 90/06136 (Schering).
Vromans et al., "Effect of Solvents on Rectal Absorption Rate of Paracetamol in Man: an in vitro Approach", International Journal of Pharmaceutics, 26 (1985) pp. 5-13.
Moolenaar et al., "Rectal Versus Oral Absorption of Diflunisal in Man", International Journal of Pharmaceutics, 19 (1984) pp. 161-167.
Moolenaar et al., "Rectal Absorption of Methadone from Dissolution-Promoting Vehicles", International Journal of Pharmaceutics, 33 (1986) pp. 249-252.
Lashmar et al., "Topical Application of Penetration Enhancers to the Skin of Nude Mice: a Histopathological Study," Journal of Pharmaceutics, 41 (1988) pp. 118-121.
Moolenaazr et al., "Manipulation of Rectal Absorption Rate of Phenytoin in Man," Pharmaceutisch Weekblad Scientific Edition, 3 (1981) pp. 175-180.

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