Pharmaceutical preparation

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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Details

C435S006120, C435S325000, C435S375000, C514S04400A

Reexamination Certificate

active

07897751

ABSTRACT:
A pharmaceutical preparation comprises nano-level particles (nanospheres) of a biocompatible polymer having, as held on their surfaces, an NFκB decoy capable of binding to NFκB to inhibit its activity. With penetration of the nanoparticles inside cells, the NFκB decoy may be delivered to an affected site and the NFκB decoy may be released from the surfaces of the nanoparticles and may be thereby efficiently and specifically introduced into the affected site.

REFERENCES:
patent: 5674192 (1997-10-01), Sahatjian et al.
patent: 6200304 (2001-03-01), Schrader
patent: 6262033 (2001-07-01), Morishita et al.
patent: 7550441 (2009-06-01), Farokhzad et al.
patent: 2002/0133126 (2002-09-01), Schrader
patent: 2004/0162251 (2004-08-01), Morishita et al.
patent: 2006/0051426 (2006-03-01), Golomb et al.
patent: 2006/0241066 (2006-10-01), Tomita et al.
patent: 2006-28041 (2006-02-01), None
patent: 2006-111591 (2006-04-01), None
patent: WO2008/139473 (2008-11-01), None
Kumar et al. Biomaterials, 2004. 25:1771-1777.
Wischke et al. Journal of Controlled Release, 2006. 114:359-368.
Takeuchi, Hiromitsu et al., Bulletin of Gifu Pharmaceutical University, Jun. 30, 2005, vol. 54, p. 57-58.
Yamamoto, Hiromitsu et al., Design of Nanoparticle Carrier For Gene Delivery, Annual Report of Hosokawa Powder Technology Foundation, Japan, May 2006, No. 13, p. 17-25.
Munier, S. et al., Cationic PLA nanoparticles for DNA delivery: Comparision of three surface polications for DNA binding, protection and transfection properties, Colloid and Surfaces B: Biointerfaces, Jul. 10, 2005, vol. 43, No. 3-4, p. 163-173.
Tahara, Kohei et al., Design of Chitosan-Modified Polylactic Acid-Glycolic Acid Nanosphers Entrapping siRNA, Abstracts of Annual Meeting of the Pharmaceutical Society of Japan, Mar. 6, 2006, vol. 126th, No. 2, p. 86.
Tahara, Kohei et al., Design of Chitosan-Surface-Modified Polylactic Acid-Glycolic Acid Nanosphers for Delivery of siRNA and its Evaluation, Drug Delivery System, Jun. 2006, vol. 21, No. 3, p. 294.

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