Pharmaceutical preparation

Details Pharmaceutical preparation Pharmaceutical preparation

1993-03-25

1995-11-28

Warden, Jill

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 8, 514 21, 514 2, 525 541, 424 851, A61K 3800, A61K 4505, C08G 6391, C08G 6348

Patent

active

054708290

ABSTRACT:
Pharmaceutical compositions which release the active ingredient slowly are based upon a growth factor or hormone as active ingredient and a means for effecting slow release of the active ingredient. Means for effecting slow release of the active ingredient comprise a conjugate or mixture of a first component and a second component. The first component is a protein other than the active ingredient for binding growth factors and hormones, and the second component is a biodegradable carrier.

REFERENCES:
patent: 4469681 (1984-09-01), Brownlee
patent: 4636424 (1987-01-01), Balazs
patent: 4828563 (1989-05-01), Muller-Lierheim
patent: 4957744 (1990-09-01), della Valle
patent: 4992378 (1991-02-01), Kelly
patent: 5252713 (1993-10-01), Morgan, Jr. et al.
Schell--Fredrick et al., Eur J. Haematol. vol. 43 p. 286 (1989)-abst. only.
Sprvgel et al., Am . J. Pathol. vol. 179 p. 601 (1987)-abst. only.
Petty et al., Ann. Neurol. vol. 36 p. 244 (1994) abst. only.
Physicians Desk Reference 1994 pp. 504, 815.
R. G. Elgin et al., Pro. Natl. Acad. Sci., 84, 3254-3258, 1987.
Japanese Abstract JO 3063-299-A, Mar. 19, 1991.
Baxter, Comp. Biochem. Physical. vol. 91B, 229-235, 1988, Printed in Great Britian.

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