Pharmaceutical iodophor preparations with controlled iodine:iodi

Details Pharmaceutical iodophor preparations with controlled iodine:iodi Pharmaceutical iodophor preparations with controlled iodine:iodi

1987-01-09

1989-07-18

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Lymphokine

424667, 424669, 424672, A61K 3179, A61K 3318, A01N 5912

Patent

active

048492159

ABSTRACT:
The microbicidal effectiveness of pharmaceutical iodophor preparations comprising an organic substance which reacts with iodine to form a complex thereof, such as polyvinylpyrrolidone, iodine bound thereto in complex form, free iodine, and iodide ions, is assured by controlling the ratio of total iodine (complex bound iodine and free iodine) to iodide ions at between 2:1 and 10:1, this ratio being adjusted without chemical oxidizing agents such as iodate ions by anodic oxidation of a solution of the iodophor preparation and iodide ions. The resulting preparation can be free of chemical oxidizing ions such as iodate ions.

REFERENCES:
patent: 2706701 (1955-04-01), Beller et al.
patent: 3288708 (1966-11-01), Cordle et al.
patent: 3355386 (1967-11-01), Contor et al.
patent: 4148884 (1979-04-01), Thorogood
CRC Handbook of Chemistry and Physics, 57th Edition (1977) p. D-142.

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