Pharmaceutical hydrogel formulations, and associated drug delive

Details Pharmaceutical hydrogel formulations, and associated drug delive Pharmaceutical hydrogel formulations, and associated drug delive

1997-12-09

2000-03-21

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

514944, 424449, A61K 910, A61K 4732, A61M 3700

Patent

active

060399775

ABSTRACT:
Pharmaceutical hydrogel formulations containing polyvinyl alcohol are provided. The formulations may serve as rug reservoirs in electrotransport drug delivery systems or passive transdermal systems, or they may be used in a variety of other types of dosage forms, e.g., capsules, suppositories, aerosols, and the like. With these formulations, there is virtually no syneresis encountered upon long term storage, an advantage that derives from selecting the quantity of polyvinyl alcohol in the gel to correspond to the polymer's degree of hydrolysis.

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