Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1975-03-06
1976-08-24
Drezin, Norman A.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
A61K 31155
Patent
active
039767876
ABSTRACT:
Pharmaceutical preparations and methods of using the same to treat a host having a condition requiring vasoconstrictive therapy. The preparations comprise a pharmaceutically acceptable carrier and a guanidine compound, or non-toxic acid addition salt thereof, having the structural notation: ##SPC1##
Wherein: R.sub.1 is hydrogen or alkyl having 1-4 carbon atoms; R.sub.2 is hydrogen, hydroxy, chloro, fluoro or bromo; and R.sub.3 is hydrogen or the same as R.sub.2 when R.sub.2 is chloro, bromo or fluoro.
REFERENCES:
patent: 3681459 (1972-08-01), Hughes et al.
Dawes et al., Brit. J. Pharmac., (1950), vol. 5, pp. 65-76.
Okujima, Chemical Abstracts, 47:3923(c), (1953).
Bastian James Winslow
Enkoji Takashi
Hughes John Lawrence
Liu Robert Chung-Huan
Armour Pharmaceutical Company
Drezin Norman A.
Mybeck Richard R.
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