Pharmaceutical formulations of spiramycin

Details Pharmaceutical formulations of spiramycin Pharmaceutical formulations of spiramycin

1995-06-06

1997-12-09

Peselev, Elli

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 71, A61K 3170

Patent

active

056960956

ABSTRACT:
New formulations of spiramycin suitable for oral administration, particularly for children, comprise spiramycin and potassium acesulfame. These formulations mask the bitterness of spiramycin without adversely affecting the bioavailability or stability of the spiramycin. Preparation by wet granulation followed by dry state mixing is also disclosed.

REFERENCES:
patent: 4375468 (1983-03-01), Dunn
patent: 5082653 (1992-01-01), Pan et al.
patent: 5403594 (1995-04-01), Calvo et al.
Publ Citation/Patent Marcel Dekker, Inc. (New York), pp. 2-3, 96-99 (1986), Authors/Inventors or Assignee O'Brien Nabors Gelardi, Patent/Publ Title, Alternative Sweetners.
Publ Citation/Patent Chemical Abstracts, vol. 115, No. 115;57213u, p. 498 (1991), Authors/Inventors or Assignee Del Rio Alvarez, Calvo Matoe, Esteban Morales, Patent/Publ Title Water-dispersible spiramycin formulations.

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