Pharmaceutical formulations of plasminogen activator proteins

Details Pharmaceutical formulations of plasminogen activator proteins Pharmaceutical formulations of plasminogen activator proteins

1989-01-27

1990-12-25

Stone, Jacqueline

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

424 9463, A61K 37547

Patent

active

049801651

ABSTRACT:
Pharmaceutical formulations for intravenous bolus injection are presented that provide thrombolytic proteins, especially "second generation" tPA molecules, in relatively high concentrations at low concentrations of excipients.

REFERENCES:
patent: 4244943 (1981-01-01), Yamahira et al.
patent: 4505893 (1985-03-01), Mori et al.
patent: 4650678 (1987-03-01), Fuhge et al.
patent: 4777043 (1988-10-01), Bennett et al.
patent: 4857320 (1989-08-01), Wittwer
patent: 4898826 (1990-02-01), Duffy et al.

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