Pharmaceutical formulations of cefaclor

Details Pharmaceutical formulations of cefaclor Pharmaceutical formulations of cefaclor

1995-10-13

1999-01-19

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Gas produced in situ by chemical reaction

424464, 424465, 424466, 514960, 514200, A61K 920, A61K 946, A61K 31545

Patent

active

058611410

ABSTRACT:
Pharmaceutical formulations of cefaclor, suitable for the direct-compression manufacture of dispersible tablets, containing the antibiotic cefaclor in an amount between 35% and 50% by weight of the total weight of the formulation, along with suitable excipients and coadjuvants selected from disintegrators, diluents, lubricants, antiadherents, sweeteners, fragrances and, optionally, flavorings, opacifiers and colorants. Said formulations are suitable for the manufacture of dispersible tablets which disintegrate in less than three minutes in water at 19.degree.-21.degree. C., and are suitable for the treatment of infections caused by bacteria strains sensitive to cefaclor.

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