Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1980-05-16
1982-11-23
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
H61K 31435
Patent
active
043605230
ABSTRACT:
This invention concerns novel water-soluble compositions of 4'-(9-acridinylamino)-methanesulfon-m-anisidide (m-AMSA). More particularly, water-soluble compositions are provided which comprise a mixture of m-AMSA with lactic acid. The compositions enable m-AMSA to be administered as an aqueous solution without the necessity of using dimethylacetamide as a pharmaceutical vehicle.
REFERENCES:
Cain et al., Europ. J. Cancer, 10:539-540, (1974).
Chemical Abstracts 67:14819u, (1967).
Weiss et al., Cancer Clin. Trials 3:203-209, 1980.
FDC Reports, Nov. 3, 1980, pp. 6-7.
Issell, Cancer Treatment Reviews (198) 7, 73-83.
Von Hoff et al., Cancer Treatment Reports 62(10), 1421-1426, (Oct. 1978).
Bouzard Daniel
Kaplan Murray A.
Perol Claude
Stemer Jacques
Weber Abraham
Bristol-Myers Company
Goldberg Jerome D.
Morse David M.
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