Pharmaceutical formulations of...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Reexamination Certificate

active

07868016

ABSTRACT:
A pharmaceutical formulation suitable for multi-dose administration comprising endo-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-1-methyl-1H-indazole-3-carboxanide hydrochloride, a preservative selected from the group consisting of alkyl paraben and phenol, and a buffer selected from the group consisting of acetate and phosphate buffers is disclosed.

REFERENCES:
patent: 4886808 (1989-12-01), King
patent: 5935972 (1999-08-01), Naylor et al.
patent: 6239147 (2001-05-01), Obach et al.
patent: 6294548 (2001-09-01), James
patent: 2004/0022755 (2004-02-01), Kamath
patent: 2005/0142073 (2005-06-01), Watts et al.
patent: 2005/0186637 (2005-08-01), Yu et al.
patent: WO 03/003957 (2003-01-01), None
patent: WO 2005/056008 (2005-06-01), None
Physicians' Desk Reference, 56thedition (2002), p. 2986.
Rowe, R.C. et al., “Handbook of pharmaceutical excipients,” 4th edition 2003, Pharmaceutical Press, XP002403743; pp. 390-394; p. 391, paragraph Stability and Storage Conditions pp. 526-528.

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