Pharmaceutical formulations comprising vegetal material...

Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution... – Containing or obtained from a bark

Reexamination Certificate

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Details

C424S725000, C514S906000, C514S929000

Reexamination Certificate

active

06335039

ABSTRACT:

FIELD OF THE INVENTION
The present invention refers to the use of vegetal material selected from Trichilia for the preparation of pharmaceutical compositions.
BACKGROUND OF THE INVENTION
Medicinal plants known as catuaba have recognized pharmaceutical use due to its aphrodisiac activities, as a tonic and in the treatment of physical and mental fatigues.
Phytotherapic formulations prepared from such plants extracts are already known from the prior art, in which these specific extracts may used alone or in association with other medicinal plant extracts, such as the Brazilian shrub (
Paullinia cupana
). Several alternative formulations comprising extracts from other catuaba species have already been disclosed in the art, all of them being related to the tonic activity of this particular group of plants.
SUMMARY OF THE INVENTION
The present invention refers to the use of vegetal material selected from Trichilia for the preparation of pharmaceutical formulations showing vasodilating and analgesic activities.
In another aspect the present inventions is directed to pharmaceutical compositions presenting vasodilating, analgesic or sexual stimulating activities comprising a vegetal material selected from Trichilia as the active ingredient.


REFERENCES:
patent: 829459 (1975-11-01), None
Fupi, V.W.K. and Moerk, P.C. Mafura nut oil and meal: processing and purification. 1982. JAOCS, J. Am. Oil Chem. Soc. 59, 94-98.*
Jolad, S., Hoffman, J.J., Schram, R.H., Cole, J.R., Tempesta, M.S. and Bates, B. Constituents ofTrichilia hispida. 1981. J. Org. Chem. 46, 4085-8.*
Nakatani, M., James, J.C., Nakanishi, K. Isolation and structures of trichilins, antifeedants the Southern army worm. 1981. J. Amer. Chem. Soc. 103, 1228-30.*
Zulma R. Vaz et al., “Analgesic Effect of The Herbal Medicine Catuama in Thermal and Chemical Models of Nociception in Mice”, Phytotherapy Research, vol. 11, No. 2, Mar. 1997, pp. 101-106.
Joao B. Calixto et al., “Herbal Medicine Catuama Induces Endothelium-Dependent and Independent Vasorelaxant Action on Isolated Vessels From Rats, Guinea-Pigs and Rabbits”, Phytotherapy , vol. 11, No. 1, Feb. 1997, pp. 32-38.
W.S. Garcez et al., “Sesquiterpenes from Trichilia Catigua”, Fitoterapia, vol. 68, No. 1, 1997, pp. 87-88.

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