Pharmaceutical formulations comprising human insulin and human p

Details Pharmaceutical formulations comprising human insulin and human p Pharmaceutical formulations comprising human insulin and human p

1984-12-17

1987-03-24

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

A61K 3726

Patent

active

046525475

ABSTRACT:
A pharmaceutical composition which comprises, in association with a pharmaceutically acceptable carrier, human insulin and human proinsulin in a weight ratio, human insulin to human proinsulin, of from about 1:100 to about 100:1, is useful in treating diabetics and in promoting attainment of natural hormonal homeostasis, thereby preventing or substantially diminishing or retarding diabetic complications.

REFERENCES:
patent: 4183849 (1980-01-01), Hansen et al.
Oyer, et al., J. Biol. Chem. 246, 1375-1386 (1971).
Yu, et al., J. Biol. Chem. 248, 3753-3761 (1973).
Horwitz, et al., J. Clin. Invest. 55, 1278-1283 (1975).
Kitabchi, Metabolism 26, 547-587 (1977).
Yanaihara, et al., Diabetes 27 (Suppl. 1), 149-160 (1978).
Yanaihara, et al., Characterization of Synthetic Human Proinsulin and C-Peptide, Proinsulin, Insulin, C-Peptide 41-49 (Excerpta Medica, 1979).
Rees, et al., Diabetes 18, 341 (1969).
Galloway, et al., Diabetes 18, 341 (1969).
Galloway, et al., J. Lab. Clin. Med. 78, 991-992 (1971).
Kitabchi, South. Med. J. 65, 833-838 (1972).
Low, et al., Nature 248, 339-340 (1974).
Starr, et al., J. Clin. Endocrinol. Metab. 38, 305-308 (1974).
Tompkins et al., Diabetologia 20, 94-101 (1981).
Fineberg, et al., Diabetes 22, 676-686 (1973).

Affiliated with

Also associated with

Rating

Pharmaceutical formulations comprising human insulin and human p does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical formulations comprising human insulin and human p, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical formulations comprising human insulin and human p will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1354001