Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1999-01-11
2000-10-24
Jordan, Kimberly
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514380, 514631, 514637, 514784, 514970, A61K 3142, A61K 31155, A61K 4700
Patent
active
061368334
ABSTRACT:
Provided is a pharmaceutical composition comprising a tablet or capsule containing a pharmacologically effective amount of a pharmaceutical compound, or a pharmaceutically acceptable salt thereof, having an amidine-based group and an optional ester group, a pharmaceutically acceptable solid carrier, and a pharmaceutically acceptable acid in an amount to modify the pH of the composition to substantially that of the compound at pH of maximum stability.
Such a composition is prepared by adding water during formulation manufacture and contacting the compound during formulation manufacture with a pharmaceutically acceptable acid having a pH in a saturated aqueous solution substantially that of the compound at pH of maximum stability.
REFERENCES:
patent: 3670085 (1972-06-01), Pryor et al.
Drugs of the Future, 22(5):508-517, 1997.
Remington's Pharmaceutical Sciences, 18th Edition, Mack Publishing Company, pp. 253-255, 1507-1508, 1990.
CA 87:189363, Larsen et al., 1977.
CA 89:204096, Zalipsky et al., 1978.
CA 104:213094, Chen et al., 1986.
Badawy Sherif Ibrahim Farag
Gilbert Donna Lynn
Black Robert W.
DuPont Pharmaceuticals Company
Jordan Kimberly
Rubin Kenneth B.
LandOfFree
Pharmaceutical formulations and process for their preparation does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pharmaceutical formulations and process for their preparation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical formulations and process for their preparation will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1964472