Pharmaceutical formulation having enhanced bile acid binding aff

Details Pharmaceutical formulation having enhanced bile acid binding aff Pharmaceutical formulation having enhanced bile acid binding aff

1995-05-30

1996-10-29

Nutter, Nathan M.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Aftertreated polymer

424528, A61K 3174, B29C 4900

Patent

active

055694527

ABSTRACT:
A pharmaceutical formulation comprising a polymeric resin having bile acid binding properties in combination with at least one bile acid binding material which enhances the bile acid binding affinity and/or capacity of the formulation, methods for preparing the formulations and methods for using the formulations.

REFERENCES:
patent: 3692895 (1972-09-01), Nelson et al.
Zhu et al., JMS-Pure Appl. Chem., A29(9), pp. 711-721, (1992).
Tan et al., "Studies on complexation between .beta.-cyclodextrin and bile salts" Int. J.Pharm., 74:127-135 (1991).
De Simone et al., J. of Pharm. Sci., vol. 67, #12, Dec. 1978, pp. 1695-1697.
Benson et al., J. of Pharm. Sci., vol. 82, 1, (1993), pp. 80-89.
Benson et al., "In vitro studies to investigate the reasons for the low potency of cholestgramine & colestipol" J. Pharm. Sci., 1993, vol. 82, #1, pp. 80-86.
Antenucci et al., "Enzymatic Degradation of .alpha.- and .beta.-Cyclodextrins . . . " J. Agric. Food. Chem., 32:1316-1321 (1984).
De Caprio et al., "Bile acid and sterol solubilization in 2-hydroxypropyl-.beta.-cyclodextrin" J. Lipid.Res., 33:441-443 (1992).
Miyajima et al., "Interaction of .beta.-Cyclodextin with Bile Salts in Aqueous Solutions" Chem. Pha,m.Bull., 34:1395-1398 (1986).
Szejtli, J. "Cyclodetrins in Drug Formulations: Part I" Pharmaceutical Technology, 24-38 (1991).

Affiliated with

Also associated with

Rating

Pharmaceutical formulation having enhanced bile acid binding aff does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical formulation having enhanced bile acid binding aff, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical formulation having enhanced bile acid binding aff will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1784267