Pharmaceutical formulation containing azapropazone

Details Pharmaceutical formulation containing azapropazone Pharmaceutical formulation containing azapropazone

1989-06-19

1991-07-23

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514243, A61K 3170, A61K 3153

Patent

active

050343793

ABSTRACT:
A pharmaceutical formulation comprising azapropazone, a pharmaceutically-acceptable metabolizable carbohydrate, and a solubilizing agent which is a carboxylate of an alkali metal, alkaline earth metal, or ammonium, wherein the minimum molar ratio of carbohydrate to azapropazone is 1:1, the minimum molar ratio of carboxylate to azapropazone is 1:1, and the pH of an aqueous solution of said formulation is within the range 2 to 8.

REFERENCES:
patent: 4440762 (1984-04-01), Rainsford et al.
Rainsford, K. D., Agents and Actions 7(5-6), 573-7, (1977), "The Comparative Gastric Ulcerogenic Activities of Non-Steroidal Anti-Inflammatory Drugs".

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