Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form
Patent
1987-07-09
1989-01-31
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
514937, 514939, 514943, A61K 910, A61K 914, A61K 4700
Patent
active
048014559
ABSTRACT:
A pharmaceutical formulation for the parenteral, in particular intravenous, administration of sparingly soluble substances is obtained when the very finely ground substance, with a maximum particle diameter of 3 .mu.m, is dispersed in an oil phase which contains emulsifier, and this mixture is emulsified with water for injection, is rendered isotonic and is homogenized using a high-pressure homogenizer, so that the resultant product is a solid/liquid/liquid disperse system.
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Mizushima et al CA.102:137811j (1985) of EPO 129435. Dec. 27, 1984.
Hansrani et al., Journal of Parenteral Science and Technology, vol. 37 No. 4, 1988, pp. 145-150.
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Kraemer Hans P.
List Paul H.
Perschbacher Harald
Schmidt Peter C.
Sedlacek Hans H.
Behringwerke Aktiengesellschaft
Rose Shep K.
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