Pharmaceutical formulation

Details Pharmaceutical formulation Pharmaceutical formulation

1990-04-27

1993-07-06

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Food or edible as carrier for pharmaceutical

424466, 424468, 424470, A61K 968

Patent

active

052251977

ABSTRACT:
A chewable tablet comprises a medicament dispersed in a chewable base, such as mannitol, together with an effervescent couple, such as citric acid - sodium bicarbonate. The combination of effervescence and chewability with optional flavorings improves the taste characteristics of the medicament in oral adminstration. A disintegrant such as microcrystalline cellulose may be added to give the patient the option of dispersing the tablet in water.

REFERENCES:
patent: 3039922 (1962-06-01), Berger et al.
patent: 4127645 (1978-11-01), Witzel et al.
patent: 4639368 (1987-01-01), Niazi et al.
patent: 4704269 (1987-11-01), Korab
patent: 4806358 (1989-02-01), Khan
patent: 4832956 (1989-05-01), Gergely
patent: 4851226 (1989-07-01), Julian
FR-A-1, 098, 116; Societe Marocaine de Produits Chimiques et Agricoles Somacia; 1954.
FR-M-2,294; Les Laboratories Dausse; 1964; pp. 1-3.

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