Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules
Patent
1992-09-30
1994-12-20
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Capsules
424469, 424489, A61K 954
Patent
active
053744306
ABSTRACT:
The residence time in the human stomach of a pharmaceutical, gastric controlled release unit can be increased significantly if the units has a density that is much higher than normal. A preferred oral dosage form according to the invention comprises tablet. The density of the unit is preferably at least 2.5 and usually at least 2.7 g/ml and can conveniently be achieved by including at least 50% by weight of a weighting agent such as barium sulphate.
REFERENCES:
patent: 4938967 (1990-07-01), Newton et al.
Devereux Jane E.
Newton John M.
London School of Pharmacy
Page Thurman K.
Venkat Jyothsna
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