Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1995-06-05
1996-09-03
Weimar, Elizabeth C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530330, 514 12, 514 21, A61K 3807, C07K 510
Patent
active
055523854
ABSTRACT:
A pharmaceutical formulation comprising a growth hormone and Lys-Gly-Asp-Ser (SEQ ID No: 1) as additive or buffering substance shows a very high stability against deamidation, oxidation and cleavage of peptide bonds. The stability of the product allows for the storing and shipment thereof in a lyophilized state or in the form of a dissolved or re-dissolved formulation at ambient temperature.
REFERENCES:
patent: 4917658 (1990-04-01), Viswanathan et al.
Becker et al., Biotech. and Applied Biochem., vol. 9, pp. 478-87, 1987.
M. J. Kaufman, Phamaceutical Research., vol. 7, No. 3, pp. 289-93, 1990.
Gellerfors et al., Acta P.ae butted.diatr Scand [Supp], vol. 370, pp. 93-100, 1990.
Riggin et al., Analytical Biochem., vol. 167, pp. 199-209, 1987.
Houghten et al., Archives of Biochem. and Biophy., vol. 178, pp. 350-55, 1977.
Becker et al. Biotech. and Applied Biochem., vol. 10, pp. 326-37, 1988.
Teh et al, The J. of Biological Chem., vol. 262, No. 14, pp. 6472-77, 1987.
Johnson et al., The J. of Biological Chem., vol. 264, No. 24, pp. 14262-71, 1989.
Manning et al. Pharmaceutical Research, vol. 6, No. 11, pp. 903-18, 1989.
Wang et al., J. of Parenteral Science and Technology, vol. 42, pp. S3-S27, 1988.
Jensen et al., Biotech. and Bioengineering, vol. 36, No. 1, pp. 1-11, 1990.
Balschmidt Per
Christensen Thorkild
Olsen Ole
S.o slashed.rensen Hans
Thim Lars
Agris Cheryl H.
Gupta Anish
Novo Nordisk A S
Weimar Elizabeth C.
Zelson Steve T.
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