Pharmaceutical fominoben/theophylline complex

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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544118, A61K 31535, C07D41302

Patent

active

041973003

ABSTRACT:
Fominoben/theophylline complex is disclosed having the formula: ##STR1## In pharmaceutical oral preparation (dragees or syrup) having respiratory analeptic or anti-tussive usage the complex is usable in dosages corresponding to those of Fominoben hydrochloride, without exhibiting, however, a bitter nauseating taste.
The complex is prepared by refluxing a solution of Fominoben hydrochloride and theophylline sodium salt in equimolar proportions in an alcoholic solvent while at the same time dehydrating the reflux stream.

REFERENCES:
"The Merck Index" 9th ed. (1976) pp. 544 and 1196.

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