Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1981-06-09
1983-10-18
Torrence, Dolph H.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
260465F, 2605011, 548253, 560 53, 562463, 562464, 564169, 424304, 424308, 424316, 424317, 424324, A61K 3141, A61K 31275, C07C12175, C07D25704
Patent
active
044105371
ABSTRACT:
This invention is directed to novel ether compounds of formula (I) ##STR1## which are of value in medicine in the palliation of haemoglobinopathies, in particular sickle-cell anaemia, and also in the palliation of pulmonary dysfunction, protection from the effects of hypoxia and the radio-sensitization of tumors. The invention is also directed to methods for the preparation of the ether compounds, to pharmaceutical formulations containing them, the preparation of such formulations and the use of the compounds in human medicine. Also provided by the invention are intermediates of value in the preparation of the ether compounds, by the methods described, and the preparation of the intermediates.
REFERENCES:
patent: 3914286 (1975-10-01), Mieville
patent: 4137309 (1979-01-01), Van Duzee
Seshadri et al, Proc. Ind. Acad. Sci., 17A, pp. 16-19 (1943).
Dean et al, New England Journal of Medicine, vol. 299, pp. 752-763, 804-811 and 863-870 (1978).
Burroughts Wellcome Co.
Torrence Dolph H.
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