Pharmaceutical drug dosage forms providing different release rat

Details Pharmaceutical drug dosage forms providing different release rat Pharmaceutical drug dosage forms providing different release rat

1998-03-11

2000-05-02

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424 43, 424451, 424464, 424468, 424449, 424472, 424474, A61K 900, A61K 924, A61K 928, A61K 948, A61K 970

Patent

active

060569689

ABSTRACT:
A pharmaceutical dosage form comprises, in one portion thereof, a substantially single (+)-enantiomer of a chiral drug other than verapamil and, in another, separate portion thereof, a substantially single (-)-enantiomer of the drug wherein, in use, the different enantiomers are released at different rates from the dosage form. The dosage form is useful for administration of chiral drugs where both enantiomers have a valid pharmacological input, and where a clinical benefit may be realised by controlling the release rates of those enantiomers. Examples of such drugs include, in particular, tramadol and warfarin.

REFERENCES:
patent: 5204116 (1993-04-01), Edgren et al.

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