Pharmaceutical dronedarone composition for parenteral...

Details Pharmaceutical dronedarone composition for parenteral... Pharmaceutical dronedarone composition for parenteral...

2005-09-06

2005-09-06

Peselev, Elli (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S469000

Reexamination Certificate

active

06939865

ABSTRACT:
A subject-matter of the invention is a pharmaceutical composition for parenteral administration, characterized in that it comprises: dronedarone or one of its pharmaceutically acceptable salts as active principle; a physiologically acceptable buffer solution capable of maintaining the pH of the composition between 3 and 5; a physiologically acceptable water-soluble β-cyclodextrin derivative.

REFERENCES:
patent: 5985915 (1999-11-01), Frangin et al.
Verduyn, S.C.; Vos, Ma; Leunissen, H.D.; “Evaluation of the acute electrophysiologic effects of intraveneous Dronedarone . . . ”; Journal of Cardiovascular Pharmacology, vol. 33, no. 2, 1999, pp 212-222; XP001024499, p 213, col. 2, lines 44-62.
Manning, A; Thisse, V.; Hodeige, D.; “SR33589, a new amiadarone-like antiarrhythmic agent . . . ”; Journal of Cardiovascular Pharmacology, vol. 25, no. 2, 1995, pp 252-261; XP001024497, p 253, col. 2, lines 1-18.

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