Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases
Patent
1992-11-23
1994-07-05
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Hydrolases
424 941, 424 9463, 424 946, A61K 37547, A61K 3748, A61K 3754
Patent
active
053265629
ABSTRACT:
Methods and pharmaceutical compositions for treatment of inflammation and arthritis using protease nexin-I as an active ingredient are disclosed.
REFERENCES:
patent: 5006252 (1991-04-01), Scott et al.
patent: 5112608 (1992-05-01), Scott et al.
McGuire-Goldring et al., Arthritis & Rheumatism, p. S24, abstract #51 (1984).
Baker et al., J. of Cellular Physiology, vol. 112, (1982), pp. 291-297.
Conn, P. (ed), The Receptors, vol. III, published by Academic Press Inc., "Protease Nexins: Secreted Protease Inhibitors that Regulate Protease Activity at or Near the Cell Surface," chapter 5, pp. 153-172 (1986).
Bozicevic Karl
Dadio Susan M.
Incyte Pharmaceuticals Inc.
Robinson Douglas W.
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