Pharmaceutical dosage unit for rectal administration

Details Pharmaceutical dosage unit for rectal administration Pharmaceutical dosage unit for rectal administration

1994-03-24

1995-07-18

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424434, 424456, 424465, 424489, 514882, 514966, A61K 948

Patent

active

054339588

ABSTRACT:
A pharmaceutical dosage unit defined by a sheath composed of a bioadhesive material which surrounds one or more capsules and one or more nonliquid supports containing the active pharmaceutical ingredient. The capsules are made of a mixture of approximately 70% gelatin and 30% glycerin. The supports can be tablets. The dosage unit is useful in providing a sustained release effect of the pharmaceutical ingredient in the lower part of the rectum for a period of 24 hours.

REFERENCES:
patent: 3577512 (1971-05-01), Shepherd et al.
patent: 3851051 (1974-11-01), Miskel et al.
patent: 4406896 (1983-09-01), Higuchi et al.
patent: 4708834 (1987-11-01), Cohen et al.
patent: 4894239 (1990-01-01), Nonomura et al.
patent: 4938967 (1990-07-01), Newton et al.
patent: 5182270 (1993-01-01), Musson et al.
patent: 5271946 (1993-12-01), Hettche

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