Pharmaceutical dosage formulations of fenofibrate and their appl

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules

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424455, 424456, 514962, 514975, A61K 948

Patent

active

058275363

ABSTRACT:
Soluble fenofibrate (Rec. INN) formulations exhibiting a significantly improved bioavailability after oral administration ("superbioavailability"), a process for their production and medicaments comprising these formulations. The said fenofibrate pharmaceutical dosage formulations essentially contain fenofibrate in solution in a solubilizing agent consisting of a non-ionic surfactant, diethylene glycol monoethyl ether (DGME).

REFERENCES:
Chemical Abstracts, vol. 112, No. 8, Feb. 19, 1990 & 5th Congr. Int. Technol. Pharm., vol. 3, 1989, pp. 190-199. A. Ben-Amor et al., "Augmentation of the Bioavailability of a Hypolipemic Agent for Incorporation into a Liquid-Containing Gel".

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