Pharmaceutical dosage forms

Details Pharmaceutical dosage forms Pharmaceutical dosage forms

1991-11-12

1993-07-20

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Aftertreated polymer

424474, 424480, 424489, 424501, 424464, 424468, A61K 916, A61K 922, A61K 936

Patent

active

052291081

ABSTRACT:
Solid pharmaceutical slow release dosage forms of dihydropyridines such as nifedipine or nimodipine are manufactured by dissolving the dihydropyridine and polyvinylpyrollidone (PVP) in a solvent, adding colloidal silicon dioxide stepwise to the resultant viscous liquid until a granular mass is formed, drying the mass, and blending the product with an excipient.

REFERENCES:
patent: 4167558 (1979-09-01), Sheth et al.
patent: 4412986 (1983-11-01), Kawata et al.
patent: 4499066 (1985-02-01), Moro et al.
patent: 4562069 (1985-12-01), Hegasy et al.
patent: 4778816 (1988-10-01), Abe et al.
patent: 4880623 (1989-11-01), Piergiorgio et al.
patent: 4882144 (1989-11-01), Hegasy
patent: 4942040 (1990-07-01), Ragnarsson et al.
patent: 5015479 (1991-05-01), Mulligan et al.

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