Pharmaceutical dosage form and method for the production...

Details Pharmaceutical dosage form and method for the production... Pharmaceutical dosage form and method for the production...

2003-01-30

2010-11-16

Sheikh, Humera N (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

C424S422000, C424S443000, C424S449000, C424S451000, C424S452000, C424S465000, C424S468000, C424S489000

Reexamination Certificate

active

07833546

ABSTRACT:
The invention relates to a method for producing a pharmaceutical dosage form as tablets, pellets and/or in the form of an active ingredient-containing matrix, whereby the tablets, pellets and/or active ingredient-containing matrix contain a pharmaceutical active ingredient and a copolymer serving as a coating agent and/or binding agent, and optionally contain a core and pharmaceutically common additives. According to the invention, the copolymer, the pharmaceutical active ingredient, the optionally present core and/or the pharmaceutically common additives are processed using known techniques by melting, injection molding, extrusion, wet granulation, casting, dipping, spreading out, spraying on, or pressing to form tablets, pellets and/or an active ingredient-containing matrix. The inventive method is characterized in that a copolymer is used that consists of 20 to 34 wt. % methacrylic acid, 20 to 69 wt. % methylacrylate and 0 to 40 wt. % ethylacrylate and, optionally, of 0 to 10 wt. % of additional vinylically copolymerizable monomers with the provision that the glass transition temperature of the copolymer is no higher than 60° C. according to ISO 11357-2, Item 3.3.3. The invention also relates to the pharmaceutical dosage form produced according to this method, said copolymer and the use thereof.

REFERENCES:
patent: 5548033 (1996-08-01), Vetter et al.
patent: 5644011 (1997-07-01), Lehmann et al.
patent: 5705189 (1998-01-01), Lehmann et al.
patent: 5837780 (1998-11-01), Albrecht et al.
patent: 5993849 (1999-11-01), Assmus et al.
patent: 6040387 (2000-03-01), Albrecht et al.
patent: 6063399 (2000-05-01), Assmus et al.
patent: 6287470 (2001-09-01), Vetter et al.
patent: 6555195 (2003-04-01), Zietek et al.
patent: 6576255 (2003-06-01), Petereit et al.
patent: 6632454 (2003-10-01), Beckert et al.
patent: 6803416 (2004-10-01), Schultes et al.
patent: 6878387 (2005-04-01), Petereit et al.
patent: 2002/0160042 (2002-10-01), Petereit et al.
patent: 2003/0060381 (2003-03-01), Meier et al.
patent: 2003/0152627 (2003-08-01), Beckert et al.
patent: 2004/0104501 (2004-06-01), Petereit et al.
patent: 2005/0019381 (2005-01-01), Petereit et al.
patent: 2005/0089571 (2005-04-01), Beckert et al.
patent: 2005/0154165 (2005-07-01), Petereit et al.
patent: 704 207 (1996-04-01), None
U.S. Appl. No. 10/532,831, filed Apr. 26, 2005, Petereit, et al.
U.S. Appl. No. 10/512,860, filed Nov. 15, 2004, Petereit, et al.
U.S. Appl. No. 09/515,098, filed Feb. 29, 2000, Assmus, et al.
U.S. Appl. No. 09/868,644, filed Jun. 28, 2001, Hoess, et al.
E. Penzel, et al. “The glass transition temperature of random copolymers:1. experimental data and the gordon-taylor equation”, POLYMER , vol. 38, No. 2, pp. 325-337 1997.

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