Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1998-04-08
2000-10-31
Russel, Jeffrey E.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424 49, 4242781, 4242801, 424451, 424464, 514 9, 514 11, 514 17, 514 18, 514 19, A61K 900, A61K 908, A61K 3805, A61K 3807, A61K 3812
Patent
active
061398624
ABSTRACT:
Methods are provided for the therapy of immunodeficient, immunodepressed or hyperactive immune states and for the prevention and treatment of opportunistic infections in such states comprising administering to a subject a pharmaceutically acceptable composition comprising as an active ingredient the dipeptide L-Ile-L-Trp, linear and cyclic monomers and polymers thereof, and/or pharmaceutically acceptable salts thereof.
REFERENCES:
patent: 4079127 (1978-03-01), Goldstein et al.
patent: 4389343 (1983-06-01), Horecker
patent: 4396605 (1983-08-01), Birr
patent: 4466918 (1984-08-01), Birr et al.
patent: 4752602 (1988-06-01), Lipsky et al.
patent: 4910296 (1990-03-01), Birr et al.
patent: 5036052 (1991-07-01), Ozeki et al.
patent: 5143903 (1992-09-01), Polita et al.
patent: 5538951 (1996-07-01), Morozov et al.
patent: 5770576 (1998-06-01), Morozov et al.
patent: 5789384 (1998-08-01), Khavinson et al.
Cecil Textbook of Medicine, 19.sup.th Edition, pp. 1785-1796 (1992).
Low et al., PNAS, 78, pp. 1162-1166 (1981).
Experientia, vol. 42, No. 5, May 1986, Basel CH, pp. 521-530, G.H. Werner et al.,, "Immunomodulating peptides".
Goodman & Gilman, "The Pharmacological Basis of Therapeutics," 6.sup.th Ed. APP III pp. 1738-1740 (1980).
Dayhoff, "Atlas of Protein Sequence and Structure," vol. 5 (1972), pp. 89-99.
Ho, Science, vol. 272, pp. 1124-1125 (May 24, 1996).
Mellors et al., Science, vol. 272, pp. 1167-1170 (May 24, 1996).
Fox, Biotechnology, vol. 12, p. 178 (Feb. 1994).
Haynes, et al., Ann. Med., vol. 28, pp. 39-41 (1996).
Rodionov et al, Immunocorrective Therapy for Pyodermas . . . Vestn. Dermatol. Venerol. vol. 1, pp. 42-45, 1990.
Hirschman et al. The Contrailed Synthesis of Peptides . . . J. Org. Chem. vol. 32, pp. 3415-3425, Nov. 1967.
Khavinson Vladimir Khatskelevich
Morozov Vyacheslav Grigorievich
Sery Sergy Vladimirovich
Cytran, Inc.
Russel Jeffrey E.
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