Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices
Patent
1988-02-09
1989-03-21
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Matrices
424 78, 424422, 424424, 424425, 424443, 424445, A61K 914
Patent
active
048141844
ABSTRACT:
Improved pharmaceutical delivery devices which can deliver hydrophilic or polar pharmaceutically active materials, as well as optionally hydrophobic or non-polar materials, have small particles with on average a diameter below 20 microns of a drug component comprising the hydrophilic or polar pharmaceutically active material, dispersed in a silicone matrix. These devices are produced by using certain organopolysiloxane-polyoxyalkylene copolymers. Preferably an emulsion of the drug component in a silicone containing composition is made before curing the composition to an elastomer.
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Aguadisch Louis M. J.
Rankin Frank S.
Cornwall Susan M.
Dow Corning Ltd.
Page Thurman K.
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