Pharmaceutical controlled release tablets containing a carrier m

Details Pharmaceutical controlled release tablets containing a carrier m Pharmaceutical controlled release tablets containing a carrier m

1996-08-19

1999-03-23

Harrison, Robert H.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424468, 514960, A61K 922, A61K 4736, A61K 4738

Patent

active

058856153

ABSTRACT:
Disclosed is a pharmaceutical controlled release tablet containing an active ingredient in combination with a carrier made of cross-linked amylose in which hydroxymethylpropylcellulose (HPMC) with a viscosity higher than or equal to 4000 cps is added as an adjuvant. The addition of HPMC to the tablet permits to control the effect of enzymes, and more particular alpha-amylase present in the intestinal medium, on the cross-linked amylose used as a carrier, and thus to reduce the dependence of the kinetics of release upon the concentration of enzymes present in the medium.

REFERENCES:
patent: 3065143 (1962-11-01), Christenson et al.
patent: 4167558 (1979-09-01), Sheth et al.
patent: 4389393 (1983-06-01), Schor et al.
patent: 4610870 (1986-09-01), Jain et al.
patent: 4704285 (1987-11-01), Alderman
patent: 4734285 (1988-03-01), Alderman et al.
patent: 4775535 (1988-10-01), Lowey
patent: 4855143 (1989-08-01), Lowey
patent: 5456921 (1995-10-01), Mateescu et al.
patent: 5603956 (1997-02-01), Mateescu et al.
patent: 5616343 (1997-04-01), Cartilier et al.
patent: 5629018 (1997-05-01), Besemer et al.
patent: 5780057 (1998-07-01), Conte et al.

Affiliated with

Also associated with

Rating

Pharmaceutical controlled release tablets containing a carrier m does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical controlled release tablets containing a carrier m, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical controlled release tablets containing a carrier m will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2122755