Pharmaceutical containing tissue protein PP4, a process for the

Details Pharmaceutical containing tissue protein PP4, a process for the Pharmaceutical containing tissue protein PP4, a process for the

1991-02-01

1992-03-17

Schain, Howard E.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

530395, 530412, 530415, 530416, 530417, C07K 318, C07K 320, C07K 322

Patent

active

050970194

ABSTRACT:
An agent for the therapy or prophylaxis of disturbances of hemostasis, which contains tissue protein PP4, a process for the purification of PP4 by means of a hydrophobic adsorbent which is insoluble in water, and a process for the pasteurization of a solution containing PP4 in the presence of calcium ions and of at least one mono- or oligosaccharide or sugar alcohol and, where appropriate, of an amino acid, and the use of PP4, are described.

REFERENCES:
patent: 4507229 (1985-03-01), Bohn
patent: 4562072 (1985-12-01), Heimburger et al.
patent: 4990597 (1991-02-01), Lobermann
Reutelingsperger et al., European Journal of Biochemistry 151: 625-629 (1985).

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