Pharmaceutical compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrate esters or chalcogen analogues thereof

Reexamination Certificate

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C558S483000

Reexamination Certificate

active

07399878

ABSTRACT:
Compounds or their salts of general formula (I): A-B-N(O)swherein: s is an integer equal to 1 or 2; A=R-T1-, wherein R is the drug radical and T1=(CO)tor (X)t′, wherein X=O, S, NR1c, R1cis H or a linear or branched alkyl or a free valence, t and t′ are integers and equal to zero or 1, with the proviso that t=1 when t′=0; t=0 when t′=1; B=-TB-X2—O— wherein TB=(CO) when t=0, TB=X when t′=0, X being as above defined; X2is equal to R1B-X-R2Bradical wherein X is as above defined, R1Band R2B, equal to or different from each other, are linear or branched C1-C6alkylenes, or X2is a radical wherein two alkylene chains C1-C4are linked to nonadjacent positions of a central ring having 4 or 6 atoms, said ring being an unsaturated cycloaliphatic ring, or a saturated or aromatic heterocylic ring, containing one or two heteroatoms, equal or different, selected from O, S, N; wherein the unsaturated cycloaliphatic ring does not have aromatic character according to Huckel's rule.

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