Pharmaceutical compounds

Details Pharmaceutical compounds Pharmaceutical compounds

1994-08-11

1996-01-16

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548251, 562466, 562473, 564 84, 560142, 560100, 560138, C07D25704, C07C 69017, A61K 3122, A61K 3118

Patent

active

054849357

ABSTRACT:
Pharmaceutical compounds of the formula ##STR1## in which R.sup.1 and R.sup.3 are each C.sub.1-4 alkyl or C.sub.1-4 alkyl-carbonyl, and R.sup.2 is carboxy, tetrazolyl, C.sub.1-4 alkyl-sulphonamido or --CR.sup.4 R.sup.5 CO.sub.2 H where R.sup.4 and R.sup.5 are each hydrogen or C.sub.1-4 alkyl; provided that when R.sup.1 and R.sup.3 are both methyl and when R.sup.1 and R.sup.3 are both methylcarbonyl, R.sup.2 is not carboxy; and salts and esters thereof.

REFERENCES:
patent: 3873538 (1975-03-01), Oxford et al.
patent: 3984429 (1976-10-01), Peel et al.
patent: 3984534 (1976-10-01), Peel et al.
patent: 3987088 (1976-10-01), Hodson et al.
patent: 4244968 (1981-01-01), Friedmann
Alexander et al., "Methylation and Hydroxylation Studies on Aloe-emodin," J. Org. Chem., 45, 20-24 (1980).
Beilsteins Handbuch der Organischen Chemie, (4th ed., 3d Supp.), vol. 10, Part 5, 4787-4790, 1972.

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