Pharmaceutical compounds

Details Pharmaceutical compounds Pharmaceutical compounds

1992-10-16

1995-04-25

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546176, C07D40110, C07D40112, A61K 31475

Patent

active

054100615

ABSTRACT:
A compound having pharmaceutical activity, of the formula ##STR1## in which A is hydrogen or --(CR.sup.1 R.sup.2).sub.x R.sup.3 where x is 0 or 1 to 4, R.sup.1 and R.sup.2 are each hydrogen or C.sub.1-4 alkyl and R.sup.3 is --CN, --COOH, tetrazolyl or --CONHSO.sub.2 R.sup.4 where R.sup.4 is optionally substituted phenyl, and ##STR2## where R.sup.5 and R.sup.6 are each hydrogen, C.sub.1-4 alkyl or --(CR.sup.1 R.sup.2).sub.x R.sup.3 where x, R.sup.1, R.sup.2 and R.sup.3 are as defined above, and R.sup.7 is hydrogen, C.sub.1-4 alkyl or --(CR.sup.1 R.sup.2).sub.x R.sup.3 where x is 1 to 4, and R.sup.1, R.sup.2 and R.sup.3 are as defined above;

REFERENCES:
patent: 5089495 (1992-02-01), Crawley
patent: 5126365 (1992-06-01), Bird
patent: 5217978 (1993-06-01), Bird
patent: 5240941 (1993-08-01), Bruneau
patent: 5254581 (1993-10-01), Bruneau
patent: 5283245 (1994-02-01), Crawley
patent: 5288742 (1994-02-01), Edwards
Snyder, D. W., "Leukotriene Receptor . . . " Annu. Rev. Pharmacol. Toxicol. vol. 29, pp. 123-143, 1989.

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