Pharmaceutical compositions of sanguinaria galangal and zinc chl

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

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424 49, 424 58, 424195, A01N 5916, A01N 6500, A61K 3330, A61K 3578

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active

043351107

ABSTRACT:
A pharmaceutical composition for the treatment of periodontal and other diseases comprises zinc chloride, the active ingredients of sanguinaria and galangal, and purified water as an excipient.
Preferred proportions of the constituents are, by weight: zinc chloride 45%; sanguinaria 10.8%; galangal 7.2%; water 37%. These proportions produce a paste, and an excipient such as petroleum jelly may be added in such a proportion as to produce an ointment. Dilution may be effected by the addition of distilled water or gelatin, and a quantity of the order of 2%, by weight, of sodium carboxy-methyl cellulose may be added as a drying agent.
The pharmaceutical composition may be administered externally, as a paste or ointment, or may be provided in capsules, with gelatin crystals as a buffer, to be taken orally, or may be administered parenterally.
The pharmaceutical composition can be prepared by dissolving zinc chloride in purified water, screening and mixing sanguinaria and galangal and adding the zinc chloride solution to the mixture of sanguinaria and galangal to produce the paste.

REFERENCES:
patent: 2344830 (1944-03-01), Mohs
patent: 4160821 (1979-07-01), Sipos
Fitzpatrick; C. A., vol. 48 (1954) 13800a.
Mohs; C. A., vol. 49 (1955) 3370i.
Chopra et al.; C. A., vol. 52 (1958) 13014a.

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