Pharmaceutical compositions of insulin drug-oligomer...

Details Pharmaceutical compositions of insulin drug-oligomer... Pharmaceutical compositions of insulin drug-oligomer...

2005-03-15

2005-03-15

Russel, Jeffrey Edwin (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S784000, C530S303000

Reexamination Certificate

active

06867183

ABSTRACT:
Pharmaceutical compositions that include an insulin drug-oligomer conjugate, a fatty acid component, and a bile salt component are described. The insulin drug is covalently coupled to an oligomeric moiety. The fatty acid component and the bile salt component are present in a weight-to-weight ratio of between 1:5 and 5:1. Methods of treating an insulin deficiency in a subject in need of such treatment using such pharmaceutical compositions are also provided, as are methods of providing such pharmaceutical compositions.

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