Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Food or edible as carrier for pharmaceutical
Patent
1988-12-20
1991-10-15
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Food or edible as carrier for pharmaceutical
424438, 424437, A61K 928
Patent
active
050573195
ABSTRACT:
The present invention provides a pharmaceutical granule composition comprising cimetidine and, as a granulating agent and taste-masking agent, an ester of a polyhydroxy compound, and where desired a palatable pharmaceutically acceptable emulsifier. Particular esters are glycerol esters. The granules of the present invention can be used in the preparation of chewable tablets which have good palatability and bioavailability.
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Gottwald Eberhard F.
Machoczek Horst M.
Mayron David
Osterwald Hermann P.
Benston William
Lentz Edward T.
Page Thurman K.
Smith Kline Dauelsberg GmbH
Suter Stuart R.
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