Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Reexamination Certificate
2002-11-19
2010-11-30
Mosher, Mary E (Department: 1648)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
C034S285000, C034S286000, C034S298000, C034S284000, C159S003000, C424S209100, C424S499000
Reexamination Certificate
active
07842310
ABSTRACT:
A method of preparing a pharmaceutical composition is described, comprising 1) atomizing a liquid formulation of a therapeutic agent to produce an atomized formulation; 2) freezing said atomized formulation to form solid particles; and 3) drying said solid particles at about atmospheric pressure to produce a powder, wherein said drying is performed in the presence of vibration, internals, mechanical stirring, or a combination thereof. Another method is described, comprising 1) atomizing a liquid formulation of a therapeutic agent to produce an atomized formulation; 2) freezing said atomized formulation to form solid particles; and 3) drying said solid particles to produce a powder; wherein the atomized formulation comprises droplets having an average mean diameter of between about 35μ and about 300μ, and/or the powder comprises dried particles having an average mean diameter of between about 35μ and about 300μ. Compositions made by the above methods, and methods of using the compositions, are also described.
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Bhuta-Wills Anjana
Ford Brandi
Huang Juan
Hwang Robin
Mikszta John A.
Alston & Bird LLP
Becton Dickinson and Company
Hill Myron G
Mosher Mary E
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