Pharmaceutical compositions for use in the suppression of gastri

Details Pharmaceutical compositions for use in the suppression of gastri Pharmaceutical compositions for use in the suppression of gastri

1977-04-01

1979-02-20

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Lymphokine

424127, 424156, 424180, A61K 3178, A61K 3170, A61K 3110, A61K 3300

Patent

active

041407601

ABSTRACT:
A pharmaceutical composition for the suppression of gastric reflux comprises a low viscosity grade sodium alginate, from 0.16 to 2.60 parts by weight of sodium bicarbonate per part by weight of sodium alginate and from 0.10 to 1.04 parts by weight of calcium carbonate per part by weight of sodium alginate. These compositions may be presented in the form of dry powders which can be admixed with water to provide a palatable liquid preparation. However, preferably the compositions are presented in liquid form and a particularly preferred liquid composition comprises an aqueous medium containing 4.0 to 6.0% weight/volume of a low viscosity grade sodium alginate, 2.0 to 3.5% weight/volume of sodium bicarbonate, 1.2 to 2.0% weight/volume of calcium carbonate and 0.6 to 1.2% weight/volume of the sodium salt of an acrylic polymer cross-linked with 1% allyl-sucrose.

REFERENCES:
patent: 3326755 (1967-06-01), Sheth
patent: 3330729 (1967-07-01), Johnson, Jr.
patent: 3767794 (1973-10-01), McVean et al.
Handbook of Non-Prescription Drugs (1) - Amer. Pharm. Assoc., Wash., D.C., (1967), pp. 9 & l2.
Handbook of Non-Prescription Drugs, Fifth Ed., Amer. Pharm. Assoc., Wash., D.C., pp. 7, 9, 10, 11 & 12.
The Extra Pharmacopdeia, The Pharm. Press, London, pp. 127 & 2050.

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