Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-02-22
1993-08-31
Friedman, S. J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514402, 514561, 514929, 514411, A61K 3144, A61K 31415, A61K 3113
Patent
active
052409309
ABSTRACT:
A pharmaceutical composition which comprises a mixture of an alpha-2 adrenoceptor antagonist, preferably idazoxan, or a pharmaceutically acceptable salt thereof, and either a catecholamine precursor or an inhibitor of aromatic L-amino acid decarboxylase, preferably carbidopa. The compositions can be used for treatment of endogenous depression or low blood pressure.
REFERENCES:
CA:111 No. 167239g-Hsu et al.
CA:107 No. 162048 b-Nishino, et al.
Al-Damluji et al., J. Endocrinol. Invest., 10 (Suppl. 3), 1987.
Al-Damluji et al., British J. Pharmacol., (1988) 95, 405-412.
Al-Damluji et al., J. Endocrinol., Supplement 117; presented at 7th joint meeting of British Endocrine Societies, Executer, Apr. 18-21, 1988.
Al-Damluji et al., "Activation of Endogenous Catecholamines Stimulates ACTH Secretion in Man," 8th Int. Congress of Endocrin., Kyoto, Japan, Jul. 17-23, 1988.
Criares T. J.
Friedman S. J.
National Research Development Corporation
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