Pharmaceutical compositions for treating bone lesions in...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

Reexamination Certificate

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Reexamination Certificate

active

06987100

ABSTRACT:
Pharmaceutical compositions for treating bone lesions in multiple myeloma or pharmaceutical compositions for treating multiple myeloma which contain as an active ingredient a compound having both of an effect of suppressing bone resorption accompanying multiple myeloma and an effect of inhibiting multiple myeloma, more particularly, 1-hydroxy-2-(imidazo[1,2-a]pyridin-3-yl)ethane-1,1-bisphosphonic acid or its salt.

REFERENCES:
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patent: 0 647 649 (1995-04-01), None
patent: WO 95/28936 (1995-11-01), None
patent: WO 99/04773 (1999-02-01), None
Kunzmann et al,Blood, 92(10, Suppl. 1, Part 1-2):279B (1998).
Berenson,Cancer, 80(8, Supplement):1661-1667 (1997).
Shipman et al,British Journal of Haematology, 98:6565-672 (1997).
Roux et al,Bone, 15(1):41-49 (1994).
Shipman et al,Leukemia and Lymphoma, 32)1-2):129-138 (1998).
Dhodapkar et al,British Journal of Haematology, 103:530-532 (1998).

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