Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...
Patent
1990-01-05
1992-01-14
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Identification or warning feature
Taste or smell or chemical irritation to the eye, nose, or...
424 944, 514311, 514456, 514474, A61K 3147, A61K 3135, A61K 3748, A61K 3750
Patent
active
050808869
ABSTRACT:
The combination of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid with a superoxide dismutase optionally containing a catalase and ascorbic acid provides enhanced protection from oxidant injury.
Administration of 6-hydroxy-2,5,7,8-tetramethyl chroman-2-carboxylic acid, SOD, and optionally CAT and/or ascorbic acid prior to or simultaneously with resuming normal blood supply to mammalian tissue following ischemia provides substantial protection from tissue damage that otherwise is observed upon reperfusion. Administration of Vitamin E, SOD, and CAT similarly provide protection from oxidant injury.
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Mickle Donald A. G.
Wu Tai-Wing
DuPont Paul E.
Hansen Philip E.
Rose Shep K.
Sterling Drug Inc.
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