Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices
Reexamination Certificate
2006-08-01
2006-08-01
Tran, S. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Matrices
C424S464000, C424S465000, C424S468000, C424S472000, C424S488000
Reexamination Certificate
active
07083807
ABSTRACT:
The invention relates to pharmaceutical compositions which can be administrated orally, allowing the controlled release of at least one active substance comprisinga) the said at least one active substance,b) between 5 and 60% by weight, relative to the total weight of the composition, of at least one excipient, selected from inert matrices, hydrophilic matrices, lipid matrices, mixtures of inert matrices and of lipid matrices, mixtures of hydrophilic matrices and of inert matrices, with the exception of mixtures comprising a polyacrylic acid and at least one hydrophilic matrix of the cellulose type;c) between 5 and 50% by weight, relative to the total weight of the composition, of at least one alkalinizing agent soluble in an aqueous phase under physiological pH conditions, selected from alkali or alkaline-earth metal hydroxidcs, carbonates, bicarbonates and phosphates, sodium borate as well as the basic salts of organic acids.It also relates to processes for the preparation of said compositions, multi-layered pharmaceutical compositions comprising at least one layer with this composition, as well as processes for the preparation of said multi-layered composition.
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Berwaer Monique
Bouquelle Anne
Deleers Michel
Fanara Domenico
Tran S.
UCB S.A.
Wenderoth , Lind & Ponack, L.L.P.
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