Pharmaceutical compositions for piperidinoalkanol-ibuprofen comb

Details Pharmaceutical compositions for piperidinoalkanol-ibuprofen comb Pharmaceutical compositions for piperidinoalkanol-ibuprofen comb

1989-04-27

1991-03-12

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424471, 424475, 424480, 424482, A61K 924

Patent

active

049992260

ABSTRACT:
The present invention is directed to a multi-layered tablet containing an ibuprofen layer, a piperidino-alkanol antihistamine layer, and a layer or layers containing conventional pharmaceutical excipients which is interspersed between the ibuprofen and piperidino-alkanol layer and serves to physically separate them. This tablet solves the problems associated with the physical and chemical incompatibilities between ibuprofen and the piperidinoalkanol antihistamines.

REFERENCES:
patent: 4552899 (1985-11-01), Sunshine et al.
patent: 4783465 (1988-11-01), Sunshine et al.
patent: 4808413 (1989-02-01), Joshi et al.
patent: 4882167 (1989-11-01), Jang
Abstract of Japanese Patent Application 137220, published Dec. 8, 1988.

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